Alternative Methods for Medical Devices: Updates on in vitro skin irritation and skin sensitisation

Biocompatibility testing is crucial for the overall safety of medical devices.

In this context, in vitro methods are becoming increasingly important. Besides a general public interest in preferring alternative methods over animal testing, it is also evident that in vitro tests are gaining more acceptance from regulatory authorities, and there is a broad consensus to replace animal testing.

The resulting changes in the testing of medical devices will affect both manufacturers and laboratories in the short to medium term. The webinar provides an overview and update on existing in vitro methods, the scientific basis and their regulatory acceptance. Additionally, case studies will be presented, and the challenges associated with testing will be discussed.

The focus is on skin irritation and sensitisation and how these endpoints can be described and evaluated using in vitro methods.