Salt or Co-Crystal Screening
Salt and co-crystal screening are reliable solutions in modern drug development to address some undesirable properties such as low solubility, chemical instability and high hygroscopicity in APIs. Utilizing High-Throughput Screening (HTS) technologies, we investigate formation of salts/co-crystals with pharmaceutically acceptable salt and co-formers in different solvent mixtures. This screening approach provides us with a quick identification of lead candidates which then will be prepared for complete characterization.
Related instruments: Unchained LabsJunior™, Bruker D8 Discover™